I can not turn on lights by app / GUI

I have a problem with my VeraPlus!

Since yesterday I can no longer turn the lights on / off via app or GUI. When I want to turn on / off the light through the app or UI it doesn’t work. When I use the hardware switch on / off it does show up in the app or user GUI. The programmable logic switches like reactor also do not work because of this problem. Who can help me? Could it be a memory problem?

rfxcom switch works fine. I have already tried to restore a backup, but it was not successful